How to Complete Diablo 4 Season 9 Journey Challenges - Infusion Affix Cancellation & Escalating Nightmares

Aug-08-2025

 

Season 9 of Diablo 4 introduces exciting new Seasonal Journey challenges, but some quests—especially those involving Horadric infusion affix cancellation and completing objectives in Escalating Nightmares—have left many players confused and frustrated. If you're struggling with these tasks, you're not alone!

 

Thanks to the vibrant Diablo community on Reddit, we've compiled a detailed, step-by-step guide with proven strategies to help you complete these challenges quickly and efficiently.

 

 

How to Complete the Infusion Affix Cancellation Challenge in Diablo 4 Season 9

One of the key Seasonal Journey objectives requires you to cancel enemy affixes by using Season 9 Horadric Infusions. This means you must attack elite enemies carrying specific affixes while your corresponding infusion is active.

 

Step-by-Step Guide

1. Equip the Horadric Infusion

   Open your inventory's Seasonal tab and equip a Horadric Infusion. Each infusion has unique powers that correspond to canceling specific enemy affixes.

 

2. Select Ideal Farming Locations

   Focus on elite-heavy areas such as Nightmare Dungeons and The Pit. These spots spawn numerous elite enemies with various affixes ideal for this challenge.

 

3. Identify Enemy Affixes

   Look for elite monsters showing affixes like Vampiric, Volcanic, and others displayed on their health bars.

 

4. Activate Your Infusion and Attack

   Ensure your infusion is active and upgraded to at least Rank 5, which is required to trigger affix cancellation.

 

5. Rotate Infusions Between Runs

   After completing cancellations for one infusion type, switch to another to progress the challenge further. Each infusion counters different affixes.

 

6. Monitor Your Progress

   Progress can be inconsistent, so expect to make multiple runs. Check your quest tracker regularly and remain patient.

 

How to Open Grand Horadric Caches and Complete Escalating Nightmare Events

The “Night Terrors” quest in Season 9 requires players to open Grand Horadric Caches inside Horadric Strongrooms during Escalating Nightmare Dungeons and to complete 5 local events with Mastery.

 

Step-by-Step Instructions:

1. Obtain and Use Legendary Nightmare Sigils

   Find Nightmare Sigils inside Horadric Strongrooms in standard Nightmare Dungeons. Use them from your consumables to start an Escalating Nightmare run.

 

2. Choose a Suitable Difficulty

   Run the dungeons at lower Torment tiers for faster clears if your main goal is quest completion rather than farming. Higher tiers are optional for better rewards.

 

3. Locate the Horadric Strongroom

   Within the Escalating Nightmare Dungeon, find the Horadric Strongroom at the end of which lies the Grand Horadric Cache.

 

4. Open the Cache to Progress

   Opening the cache completes part one of the quest. Multiple caches need to be opened depending on your quest requirements.

 

5. Complete Local Events for Mastery

   Complete 5 random local events like rescuing villagers or activating pillars within Escalating Nightmares. These are RNG-based, so multiple runs might be necessary.

 

Tip: If you lack Nightmare Sigils, join other players' Escalating Nightmare runs without needing your own sigil. Grouping up helps maintain steady progress.

 

Final Tips for Season 9 Horadric and Escalating Nightmare Challenges

Patience and strategy are key. Some challenges require multiple runs and careful farming.

Use community-tested tips to improve efficiency and reduce frustration.

Don't hesitate to team up with other players for faster progression.

 

By following this guide, you can complete these tricky Season 9 Seasonal Journey quests more smoothly and enjoy the rewards Diablo 4 has to offer.